SB399885
Product Specifications
CAS Number
402713-80-8
Target
5-HT Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Purity
0.9894
Bioactivity
SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively) .
Smiles
O(C)C1=C(C=C(S(NC2=C(OC)C(Cl)=CC(Cl)=C2)(=O)=O)C=C1)N3CCNCC3
Molecular Formula
C18H21Cl2N3O4S
Molecular Weight
446.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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