What is the catalog number for 8-Chloroadenosine?

The catalog number for 8-Chloroadenosine is T19661.

What sizes are available for 8-Chloroadenosine?

8-Chloroadenosine is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 500 mg.

How many pack sizes does 8-Chloroadenosine come in?

8-Chloroadenosine is available in 8 different pack sizes.

Is 8-Chloroadenosine in stock?

8-Chloroadenosine is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures 8-Chloroadenosine?

8-Chloroadenosine is manufactured by Molfinity.

What is the estimated delivery time for 8-Chloroadenosine?

Estimated delivery time for 8-Chloroadenosine is approximately 10 business day(s), depending on your location.

8-Chloroadenosine

Product Specifications

CAS Number

34408-14-5

Target

Autophagy, AMPK

Related Pathways

Autophagy, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling

Purity

0.9984

Bioactivity

8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Chloroadenosine (NSC-354258) is a nucleoside analog; metabolized in vivo to 8-Chloro-ATP. Incorporates into RNA during transcription and inhibits RNA synthesis. Exhibits cytotoxicity in MM.1S, RPMI-8226, and U266 cancer cell lines; induces G2/M cell cycle arrest and mitotic catastrophe in A549 and H1299 cells. 8-Chloroadenosine (NSC-354258) has been shown to deplete ATP and inhibit tumor growth in hematological malignancies as well as in lung and breast cancer cell lines.