L-779450

Product Specifications

CAS Number

303727-31-3

Target

Autophagy|||Raf

Related Pathways

Autophagy|||MAPK

Purity

0.98

Bioactivity

L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM), displays > 7, > 30 and > 70-fold selectivity over p38?, GSK3? and Lck respectively.

Smiles

Oc1cc(ccc1Cl)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1

Molecular Formula

C20H14ClN3O

Molecular Weight

347.8

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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