MK-2206 dihydrochloride
Product Specifications
CAS Number
1032350-13-2
Target
Autophagy, Apoptosis, Akt
Related Pathways
Apoptosis, Cytoskeletal Signaling, Autophagy, PI3K/Akt/mTOR signaling
Purity
0.9994
Bioactivity
MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor activity.
Smiles
Cl.Cl.NC1(CCC1)c1ccc(cc1)-c1nc2ccn3c(n[nH]c3=O)c2cc1-c1ccccc1
Molecular Formula
C25H23Cl2N5O
Molecular Weight
480.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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