AZD4547
Product Specifications
CAS Number
1035270-39-3
Target
FGFR, VEGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9988
Bioactivity
AZD4547 is an FGFR family inhibitor. AZD4547 selectively inhibits FGFR1 phosphorylation and suppresses cancer cell proliferation through inhibition of FGFR1 signaling, and is able to act on FGFR1 (IC50:0.2 nM), FGFR2 (IC50:2.5 nM), FGFR3 (IC50:1.8 nM) and FGFR4 (IC50:165 nM) . IC50:165 nM) .[2]
Smiles
COc1cc(CCc2cc(NC(=O)c3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)n[nH]2)cc(OC)c1
Molecular Formula
C26H33N5O3
Molecular Weight
463.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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