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LDN193189

Product Specifications

CAS Number

1062368-24-4

Target

ALK, TGF-beta/Smad

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells

Purity

0.9986

Bioactivity

LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 and ALK3 (IC50s: 0.8/0.8/5.3/16.7 nM for ALK1/2/3/6) .

Smiles

C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12

Molecular Formula

C25H22N6

Molecular Weight

406.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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