LDN193189
Product Specifications
CAS Number
1062368-24-4
Target
ALK, TGF-beta/Smad
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells
Purity
0.9986
Bioactivity
LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 and ALK3 (IC50s: 0.8/0.8/5.3/16.7 nM for ALK1/2/3/6) .
Smiles
C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12
Molecular Formula
C25H22N6
Molecular Weight
406.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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