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GBR 12783 dihydrochloride

Product Specifications

CAS Number

67469-75-4

Target

Others, Dopamine Receptor

Related Pathways

Others, GPCR/G Protein, Neuroscience

Purity

0.9808

Bioactivity

GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.

Smiles

N1(CCN(CC1)CC=CC2=CC=CC=C2)CCOC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl

Molecular Formula

C28H34Cl2N2O

Molecular Weight

485.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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