GBR 12783 dihydrochloride
Product Specifications
CAS Number
67469-75-4
Target
Others, Dopamine Receptor
Related Pathways
Others, GPCR/G Protein, Neuroscience
Purity
0.9808
Bioactivity
GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.
Smiles
N1(CCN(CC1)CC=CC2=CC=CC=C2)CCOC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl
Molecular Formula
C28H34Cl2N2O
Molecular Weight
485.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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