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Filgotinib

Product Specifications

CAS Number

1206161-97-8

Target

HIV Protease|||JAK|||Tyrosine Kinases

Related Pathways

Stem Cells|||JAK/STAT signaling|||Microbiology/Virology|||Angiogenesis|||Proteases/Proteasome|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

Purity

0.9979

Bioactivity

Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 values of 10 nM for JAK1, 28 nM for JAK2, 810 nM for JAK3, and 116 nM for TYK2.

Smiles

O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1

Molecular Formula

C21H23N5O3S

Molecular Weight

425.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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