CRIPGBM
Product Specifications
CAS Number
2361988-76-1
Target
Apoptosis, RIP kinase, TNF
Related Pathways
Apoptosis, NF-κB
Bioactivity
CRIPGBM, a proapoptotic derivative of RIPGBM, selectively induces apoptosis in GBM cancer stem cells (CSCs) by targeting receptor-interacting protein kinase 2 (RIPK2), demonstrating an EC50 of 68 nM in GBM-1 cells [1].
Smiles
C([N+]=1C2=C(N(CC3=CC=CC=C3)C1C)C(=O)C=4C(C2=O)=CC=CC4)C5=CC=C(F)C=C5
Molecular Formula
C26H20FN2O2
Molecular Weight
411.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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