CCR2 antagonist 4 hydrochloride

Product Specifications

CAS Number

1313730-14-1

Target

Others|||CCR

Related Pathways

Microbiology/Virology|||GPCR/G Protein|||Immunology/Inflammation|||Others

Bioactivity

CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b) . It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM) .

Smiles

Cl.FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1

Molecular Formula

C21H22Cl2F3N3O2

Molecular Weight

476.32

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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