CCR2 antagonist 4 hydrochloride
Product Specifications
CAS Number
1313730-14-1
Target
Others|||CCR
Related Pathways
Microbiology/Virology|||GPCR/G Protein|||Immunology/Inflammation|||Others
Bioactivity
CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b) . It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM) .
Smiles
Cl.FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1
Molecular Formula
C21H22Cl2F3N3O2
Molecular Weight
476.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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