Capivasertib
Product Specifications
CAS Number
1143532-39-1
Target
PKA, Akt, mTOR, Autophagy
Related Pathways
Autophagy, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
Purity
0.996
Bioactivity
Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib has antitumor activity for the treatment of breast cancer.
Smiles
NC1(CCN(CC1)c1ncnc2[nH]ccc12)C(=O)N[C@@H](CCO)c1ccc(Cl)cc1
Molecular Formula
C21H25ClN6O2
Molecular Weight
428.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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