NVP-TAE 226
Product Specifications
CAS Number
761437-28-9
Target
Apoptosis, PYK2, FAK, c-Met/HGFR, IGF-1R
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis
Purity
0.9917
Bioactivity
NVP-TAE 226 (TAE226) is a potent FAK inhibitor (IC50: 5.5 nM), exhibiting even greater efficacy against Pyk2 (IC50: 3.5 nM), and is 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.
Smiles
CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl
Molecular Formula
C23H25ClN6O3
Molecular Weight
468.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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