NVP-TAE 226

Product Specifications

CAS Number

761437-28-9

Target

Apoptosis|||PYK2|||FAK|||c-Met/HGFR|||IGF-1R

Related Pathways

Apoptosis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis

Purity

0.9917

Bioactivity

NVP-TAE 226 (TAE226) is a potent FAK inhibitor (IC50: 5.5 nM), exhibiting even greater efficacy against Pyk2 (IC50: 3.5 nM), and is 10- to 100-fold less effective against IGF-1R, InsR, c-Met, and ALK.

Smiles

CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl

Molecular Formula

C23H25ClN6O3

Molecular Weight

468.94

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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