Dinaciclib

Product Specifications

CAS Number

779353-01-4

Target

Apoptosis|||CDK

Related Pathways

Apoptosis|||Cell Cycle/Checkpoint

Purity

0.9975

Bioactivity

Dinaciclib (SCH 727965) is a selective CDK inhibitor targeting CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM) . It exhibits potential antitumor activity by inhibiting the incorporation of thoracic glycan (dThd) DNA.

Smiles

N(CC1=CN(=O)=CC=C1)C=2N3C(N=C(C2)N4[C@H](CCO)CCCC4)=C(CC)C=N3

Molecular Formula

C21H28N6O2

Molecular Weight

396.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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