Dinaciclib
Product Specifications
CAS Number
779353-01-4
Target
Apoptosis|||CDK
Related Pathways
Apoptosis|||Cell Cycle/Checkpoint
Purity
0.9975
Bioactivity
Dinaciclib (SCH 727965) is a selective CDK inhibitor targeting CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM) . It exhibits potential antitumor activity by inhibiting the incorporation of thoracic glycan (dThd) DNA.
Smiles
N(CC1=CN(=O)=CC=C1)C=2N3C(N=C(C2)N4[C@H](CCO)CCCC4)=C(CC)C=N3
Molecular Formula
C21H28N6O2
Molecular Weight
396.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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