5-HT3 antagonist 5
Product Specifications
UNSPSC Description
5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT3 agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-ht3-antagonist-5.html
Solubility
DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=NC2=CC=CC=C2N=C1)NC3=CC=C(C=C3)OC
Molecular Weight
279.29
References & Citations
[1]Mahesh R, et al. Design, synthesis and structure-activity relationship of novel quinoxalin-2-carboxamides as 5-HT3 receptor antagonists for the management of depression. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6773-6.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148038/5-HT3-antagonist-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148038/5-HT3-antagonist-5-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
901599-43-7
Available Sizes
Curated Selection
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