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LDN-212854

Product Specifications

CAS Number

1432597-26-6

Target

ALK, TGF-beta/Smad

Related Pathways

Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9938

Bioactivity

LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2 (IC50=1.3 nM) versus ALK1/3 compared to other inhibitors.

Smiles

C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12

Molecular Formula

C25H22N6

Molecular Weight

406.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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