LDN-212854
Product Specifications
CAS Number
1432597-26-6
Target
ALK, TGF-beta/Smad
Related Pathways
Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9938
Bioactivity
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2 (IC50=1.3 nM) versus ALK1/3 compared to other inhibitors.
Smiles
C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12
Molecular Formula
C25H22N6
Molecular Weight
406.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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