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Idelalisib

Product Specifications

CAS Number

870281-82-6

Target

Autophagy, PI3K

Related Pathways

PI3K/Akt/mTOR signaling, Autophagy

Purity

0.9994

Bioactivity

Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM) . The selectivity for p110δ is 40- to 300-fold than p110α/β/γ.

Smiles

[C@H](NC1=C2C(N=CN2)=NC=N1)(CC)C=3N(C(=O)C=4C(N3)=CC=CC4F)C5=CC=CC=C5

Molecular Formula

C22H18FN7O

Molecular Weight

415.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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