Inauhzin
Product Specifications
CAS Number
309271-94-1
Target
Sirtuin, MDM-2/p53
Related Pathways
Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair
Purity
0.9936
Bioactivity
Inauhzin (INZ) (INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress (IC50=3 uM, in A549 cell) .
Smiles
CCC(Sc1nnc2c(n1)[nH]c1ccccc21)C(=O)N1c2ccccc2Sc2ccccc12
Molecular Formula
C25H19N5OS2
Molecular Weight
469.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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