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XAV-939

Product Specifications

CAS Number

284028-89-3

Target

PARP, Wnt/beta-catenin

Related Pathways

Stem Cells, Chromatin/Epigenetic, Cytoskeletal Signaling, DNA Damage/DNA Repair

Purity

0.9967

Bioactivity

XAV-939 (NVP-XAV939) is a Tankyrase (TNKS) inhibitor that inhibits TNKS1 and TNKS2 (IC50=11/4 nM) . XAV-939 selectively inhibits Wnt/β-catenin-mediated transcription.

Smiles

FC(F)(F)C1=CC=C(C=C1)C1=NC(=O)C2=C(CCSC2)N1

Molecular Formula

C14H11F3N2OS

Molecular Weight

312.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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