Kobe0065
Product Specifications
CAS Number
436133-68-5
Target
Raf, Ras, Apoptosis
Related Pathways
GPCR/G Protein, Apoptosis, MAPK
Purity
>99.99%
Bioactivity
Kobe0065 is a novel and effective small-molecule compound that inhibits the Ras-Raf interaction by structure-based drug design (SBDD) ; it displays potent activity, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.
Smiles
Cc1ccc(NC(=S)NNc2c(cc(cc2[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O)cc1Cl
Molecular Formula
C15H11ClF3N5O4S
Molecular Weight
449.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1444013-01 0.02 mg (E-Coli)
Recombinant Psychrobacter cryohalolentis Pyridoxine 5'-phosphate synthase (pdxJ)
Sign In for Pricing
View Details MBS1444013-02 0.1 mg (E-Coli)
Recombinant Psychrobacter cryohalolentis Pyridoxine 5'-phosphate synthase (pdxJ)
Sign In for Pricing
View Details MBS1444013-03 0.02 mg (Baculovirus)
Recombinant Psychrobacter cryohalolentis Pyridoxine 5'-phosphate synthase (pdxJ)
Sign In for Pricing
View Details MBS1444013-04 0.02 mg (Mammalian-Cell)
Recombinant Psychrobacter cryohalolentis Pyridoxine 5'-phosphate synthase (pdxJ)
Sign In for Pricing
View Details