Sulfo-PDBA-DM4
Product Specifications
CAS Number
1461704-01-7
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Sulfo-PDBA-DM4 is a drug-linker conjugate for antibody-drug conjugate (ADC) applications, combining the potent tubulin inhibitor DM4 with the gluthatione-cleavable linker Sulfo-PDBA. This configuration harnesses DM4's cytotoxic potential through Sulfo-PDBA's targeted delivery mechanism.
Smiles
[H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)c1cc(C\C(C)=C/C=C/[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)cc(OC)c1Cl)OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCC(C(O)=O)S(O)(=O)=O |c:17,t:19|
Molecular Formula
C42H60ClN3O15S3
Molecular Weight
978.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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