SNIPER (ABL) -049

Product Specifications

Target

Others|||SNIPERs|||Bcr-Abl

Related Pathways

Angiogenesis|||Others|||Cytoskeletal Signaling|||PROTAC|||Tyrosine Kinase/Adaptors

Bioactivity

SNIPER (ABL) -049, a compound that conjugates Imatinib (ABL inhibitor) with Bestatin (IAP ligand) through a linker, effectively reduces BCR-ABL protein levels, demonstrating a DC50 of 100 ?M[1].

Smiles

CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC4=CC=CC=C4)N)=O)=O)=O)CC3)C=C2)=O)C=C1NC5=NC=CC(C6=CC=CN=C6)=N5

Molecular Formula

C52H66N10O8

Molecular Weight

959.14

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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