SNIPER (ABL) -047
Product Specifications
Target
Bcr-Abl|||SNIPERs|||Others
Related Pathways
Others|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||PROTAC
Bioactivity
SNIPER (ABL) -047, a compound that links HG-7-85-01 (an ABL inhibitor) to MV-1 (an IAP ligand) via a linker, effectively decreases the BCR-ABL protein levels, achieving a DC50 value of 2 ?M[1].
Smiles
CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCNC([C@H](C(C6=CC=CC=C6)C7=CC=CC=C7)NC([C@H]8N(C([C@@H](NC([C@H](C)NC)=O)C9CCCCC9)=O)CCC8)=O)=O)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1
Molecular Formula
C67H82F3N11O9S
Molecular Weight
1274.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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