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SNIPER (ABL) -047

Product Specifications

Target

Bcr-Abl|||SNIPERs|||Others

Related Pathways

Others|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||PROTAC

Bioactivity

SNIPER (ABL) -047, a compound that links HG-7-85-01 (an ABL inhibitor) to MV-1 (an IAP ligand) via a linker, effectively decreases the BCR-ABL protein levels, achieving a DC50 value of 2 ?M[1].

Smiles

CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCNC([C@H](C(C6=CC=CC=C6)C7=CC=CC=C7)NC([C@H]8N(C([C@@H](NC([C@H](C)NC)=O)C9CCCCC9)=O)CCC8)=O)=O)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1

Molecular Formula

C67H82F3N11O9S

Molecular Weight

1274.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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