What is the catalog number for SNIPER (ABL) -024?

The catalog number for SNIPER (ABL) -024 is T18688.

What sizes are available for SNIPER (ABL) -024?

SNIPER (ABL) -024 is available in the following size(s): 100 mg, 500 mg.

How many pack sizes does SNIPER (ABL) -024 come in?

SNIPER (ABL) -024 is available in 2 different pack sizes.

Is SNIPER (ABL) -024 in stock?

SNIPER (ABL) -024 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SNIPER (ABL) -024?

SNIPER (ABL) -024 is manufactured by Molfinity.

What is the estimated delivery time for SNIPER (ABL) -024?

Estimated delivery time for SNIPER (ABL) -024 is approximately 10 business day(s), depending on your location.

SNIPER (ABL) -024

Product Specifications

CAS Number

2222355-77-1

Target

SNIPERs, Others, Bcr-Abl

Related Pathways

Cytoskeletal Signaling, PROTAC, Tyrosine Kinase/Adaptors, Others, Angiogenesis

Bioactivity

SNIPER (ABL) -024, a compound that conjugates GNF5 (ABL inhibitor) to an LCL161 derivative (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a half-maximal degradation concentration (DC50) of 5μM[1].

Smiles

C([C@@H](NC([C@@H](NC)C)=O)C1CCCCC1)(=O)N2[C@@](CCC2)(C3=NC(C(=O)C4=CC(OCCOCCOCCOCCNC(=O)C5=CC(=CC=C5)C=6C=C(NC7=CC=C(OC(F)(F)F)C=C7)N=CN6)=CC=C4)=CS3)[H]