SNIPER (ABL) -015
Product Specifications
Target
Bcr-Abl|||Others|||SNIPERs
Related Pathways
Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Others|||PROTAC
Bioactivity
SNIPER (ABL) -015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5 ?M [1].
Smiles
O=C(NCCOCCOCCOCCNC([C@@H](NC([C@H]1N(C([C@H](C2CCCCC2)NC([C@H](C)NC)=O)=O)CCC1)=O)C(C3=CC=CC=C3)C4=CC=CC=C4)=O)C5=CC=CC(C6=NC=NC(NC7=CC=C(OC(F)(F)F)C=C7)=C6)=C5
Molecular Formula
C58H70F3N9O9
Molecular Weight
1094.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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