SJFδ
Product Specifications
CAS Number
2254609-23-7
Target
Others, p38 MAPK, PROTACs, Autophagy
Related Pathways
PROTAC, Others, Autophagy, MAPK
Bioactivity
SJFδ is a 10-atom linker PROTAC that selectively degrades p38δ with a DC50 of 46.17 nM, without degrading p38α, p38β, or p38γ[1].
Smiles
C(NC1=CC(F)=C(OC=2C3=C(C=C(OCCOCCOCCOC4=C(CNC(=O)[C@H]5N(C([C@H](C(C)C)N6CC=7C(C6=O)=CC=CC7)=O)C[C@H](O)C5)C=CC(=C4)C=8SC=NC8C)C(OC)=C3)N=CC2)C=C1)(=O)C9(C(NC%10=CC=C(F)C=C%10)=O)CC9
Molecular Formula
C62H63F2N7O12S
Molecular Weight
1168.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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