(S, R, S) -AHPC-O-Ph-PEG1-NH2
Product Specifications
CAS Number
2361117-24-8
Target
E3 Ligase Ligand-Linker Conjugate|||Others
Related Pathways
Others|||PROTAC
Bioactivity
(S, R, S) -AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is an E3 ligase ligand-linker conjugate that combines a VHL ligand for the E3 ubiquitin ligase with a PROTAC linker; it is used in PROTAC EED degrader-1, targeting EED with a potency (pKD) of 9.02[1].
Smiles
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCN)cc2)C(C)(C)C)cc1
Molecular Formula
C32H41N5O6S
Molecular Weight
623.76
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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