PR-619
Product Specifications
CAS Number
2645-32-1
Target
Autophagy, Apoptosis, DUB
Related Pathways
Cell Cycle/Checkpoint, Ubiquitination, Apoptosis, DNA Damage/DNA Repair, Autophagy
Purity
>99.99%
Bioactivity
PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor that inhibits USP2/4/5/7/8 (EC50=7.2/3.93/8.61/6.86/4.9 μM) . PR-619 induces endoplasmic reticulum stress and activates autophagy.
Smiles
Nc1nc(N)c(SC#N)cc1SC#N
Molecular Formula
C7H5N5S2
Molecular Weight
223.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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