AZD-8055

1009298-09-2

Apoptosis, Autophagy, mTOR

Apoptosis, PI3K/Akt/mTOR signaling, Autophagy

0.9969

AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells) . It is ~1,000-fold selective for mTOR over all PI3K isoforms.

C[C@@H]1N(C=2C3=C(N=C(N2)N4[C@@H](C)COCC4)N=C(C=C3)C5=CC(CO)=C(OC)C=C5)CCOC1

C25H31N5O4

465.54

Ice Packs

-20°C