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Pomalidomide-amido-C1-Br

Product Specifications

CAS Number

2351106-38-0

Target

Others, E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC, Others

Bioactivity

Pomalidomide-amido-C1-Br is a synthesized conjugate consisting of the Pomalidomide-based cereblon ligand and a linker, functioning as an E3 ligase ligand-linker. This compound serves as a tool for designing a B-Raf PROTAC degrader, specifically PROTAC B-Raf degrader 1, which exhibits anti-cancer activity[1].

Smiles

O=C(NC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3)CBr

Molecular Formula

C15H12BrN3O5

Molecular Weight

394.18

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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