Pomalidomide-amido-C1-Br
Product Specifications
CAS Number
2351106-38-0
Target
Others, E3 Ligase Ligand-Linker Conjugate
Related Pathways
PROTAC, Others
Bioactivity
Pomalidomide-amido-C1-Br is a synthesized conjugate consisting of the Pomalidomide-based cereblon ligand and a linker, functioning as an E3 ligase ligand-linker. This compound serves as a tool for designing a B-Raf PROTAC degrader, specifically PROTAC B-Raf degrader 1, which exhibits anti-cancer activity[1].
Smiles
O=C(NC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3)CBr
Molecular Formula
C15H12BrN3O5
Molecular Weight
394.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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