Phthalimide-PEG4-PDM-OTBS
Product Specifications
Target
Others, PROTAC Linker
Related Pathways
Others, PROTAC
Bioactivity
Phthalimide-PEG4-PDM-OTBS is a PROTAC linker comprised of polyethylene glycols (PEGs) utilized in the synthesis of various PROTACs, which consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein, leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].
Smiles
O=C(N1CCOCCOCCOCCO[C@@H]2C[C@@H](CO[Si](C(C)(C)C)(C)C)NC2)C3=C(C=CC=C3)C1=O
Molecular Formula
C27H44N2O7Si
Molecular Weight
536.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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