What is the catalog number for Momelotinib?

The catalog number for Momelotinib is T1849.

What sizes are available for Momelotinib?

Momelotinib is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does Momelotinib come in?

Momelotinib is available in 9 different pack sizes.

Is Momelotinib in stock?

Momelotinib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Momelotinib?

Momelotinib is manufactured by Molfinity.

What is the estimated delivery time for Momelotinib?

Estimated delivery time for Momelotinib is approximately 10 business day(s), depending on your location.

Momelotinib

Product Specifications

CAS Number

1056634-68-4

Target

JAK, Autophagy, Apoptosis

Related Pathways

JAK/STAT signaling, Chromatin/Epigenetic, Stem Cells, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, Autophagy

Purity

0.9956

Bioactivity

Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.