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BX-912

Product Specifications

CAS Number

702674-56-4

Target

PKA, PDK, Chk, VEGFR, Apoptosis, CDK

Related Pathways

Angiogenesis, Apoptosis, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint

Purity

0.9934

Bioactivity

BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM) . The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC etc.

Smiles

Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCc1cnc[nH]1

Molecular Formula

C20H23BrN8O

Molecular Weight

471.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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