Ethyl gentisate

Ethyl gentisate (Ethyl 2,5-dihydroxybenzoate) is a dual modulator for cell differentiation, that enhances the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and alkaline phosphatase activity, inhibits RANKL-activated osteoclastogenesis in RAW264.7 cells, and balances the bone remodeling process[1].

Product Specifications

CAS Number

[3943-91-7]

Product Name Alternative

Ethyl 2,5-dihydroxybenzoate

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ethyl-gentisate.html

Concentration

10mM

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=C(C=C(C=C1)O)C(OCC)=O

Molecular Formula

C9H10O4

Molecular Weight

182.17

Precautions

H315, H319, H335

References & Citations

[1]Kwon BJ, et al., Ethyl-2, 5-dihydroxybenzoate displays dual activity by promoting osteoblast differentiation and inhibiting osteoclast differentiation. Biochem Biophys Res Commun. 2016 Mar 11;471 (3) :335-41.