MC-Val-Cit-PAB-duocarmycin chloride
Product Specifications
CAS Number
2055896-98-3
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
MC-Val-Cit-PAB-duocarmycin is an antibody-drug conjugate (ADC) linker that combines duocarmycin, a potent DNA minor groove-binding alkylating agent, with an antitumor drug through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
Smiles
[Cl-].CC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(C[N+](C)(C)CCOc2ccc3[nH]c(cc3c2)C(=O)N2C[C@@H](CCl)c3c2cc(O)c2ccccc32)cc1
Molecular Formula
C54H65ClN9O9
Molecular Weight
1019.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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