MC-Val-Cit-PAB-Auristatin E
Product Specifications
CAS Number
2055896-77-8
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
MC-Val-Cit-PAB-Auristatin E is an antibody-drug conjugate (ADC) linker compound with Auristatin E, a potent cytotoxic tubulin modifier, attached via the MC-Val-Cit-PAB linker, demonstrating significant antitumor activity.
Smiles
[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H]([N+](CC3=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN4C(=O)C=CC4=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C3)(C)C)C(C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Molecular Formula
C68H108N11O13
Molecular Weight
1287.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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