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MC-Val-Cit-PAB-Auristatin E

Product Specifications

CAS Number

2055896-77-8

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

MC-Val-Cit-PAB-Auristatin E is an antibody-drug conjugate (ADC) linker compound with Auristatin E, a potent cytotoxic tubulin modifier, attached via the MC-Val-Cit-PAB linker, demonstrating significant antitumor activity.

Smiles

[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H]([N+](CC3=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN4C(=O)C=CC4=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C3)(C)C)C(C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

Molecular Formula

C68H108N11O13

Molecular Weight

1287.65

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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