MC-Sq-Cit-PAB-Dolastatin10

Product Specifications

CAS Number

1941168-65-5

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

MC-Sq-Cit-PAB-Dolastatin10 is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), incorporating Dolastatin10 (a tubulin polymerization inhibitor) connected via the MC-Sq-Cit-PAB ADC linker.

Smiles

C(N[C@H](C(NC1=CC=C(C[N+]([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N2[C@]([C@@H]([C@H](C(N[C@@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)OC)(CCC2)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)[C@@H](C)C)(C)C)C=C1)=O)CCCNC(N)=O)(=O)C5(C(NCCCCCN6C(=O)C=CC6=O)=O)CCC5