Ruxolitinib
Product Specifications
CAS Number
941678-49-5
Target
Apoptosis|||Mitophagy|||Autophagy|||JAK|||Tyrosine Kinases
Related Pathways
Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||JAK/STAT signaling|||Apoptosis|||Stem Cells|||Autophagy|||Angiogenesis
Purity
>99.99%
Bioactivity
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
Smiles
N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Molecular Formula
C17H18N6
Molecular Weight
306.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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