Ruxolitinib

Product Specifications

CAS Number

941678-49-5

Target

Apoptosis|||Mitophagy|||Autophagy|||JAK|||Tyrosine Kinases

Related Pathways

Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||JAK/STAT signaling|||Apoptosis|||Stem Cells|||Autophagy|||Angiogenesis

Purity

>99.99%

Bioactivity

Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.

Smiles

N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12

Molecular Formula

C17H18N6

Molecular Weight

306.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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