Buparlisib
Product Specifications
CAS Number
944396-07-0
Target
Apoptosis, PI3K
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling
Purity
0.9845
Bioactivity
Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ) .
Smiles
Nc1cc(c(cn1)-c1cc(nc(n1)N1CCOCC1)N1CCOCC1)C(F)(F)F
Molecular Formula
C18H21F3N6O2
Molecular Weight
410.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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SIRT1 (HST2, S. cerevisiae, Homolog of, NAD Dependent deacetylase SIRT1, NAD Dependent deacetylase Sirtuin 1, NAD Dependent Protein deacetylase Sirtuin 1, Regulatory Protein SIR2 Homolog 1, SIR1_HUMAN, SIR2 like 1, SIR2 like Protein 1, SIR2, S.cerevisiae, Homolog-like 1, SIR2-like Protein 1, SIR2ALPHA, SIR2ALPHA, SIR2alpha Protein, SIR2alpha Protein, SIR2L1, SIRT 1, Sirt1, SIRT1 Sir2 like Proteins (siruitins) Type 1, SIRT1, Sirtuin (silent mating Type information Regulation 2 Homolog) 1 (S. cerevisiae), Sirtuin (silent mating Type information regulation 2 Homolog) 1 (S. cerevisiae), SirtT1 75kD fragment, Sirtuin (silent mating Type information regulation 2 Homolog) 1 (S. cerevisiae), Sirtuin 1, Sirtuin, Sirtuin Type 1, Sirtuin Type 1)
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