Mal-C6-?-Amanitin
Product Specifications
CAS Number
1578249-76-9
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Mal-C6-?-Amanitin, an ADC (antibody-drug conjugate) linker drug, incorporates the powerful antitumor agent ?-Amanitin, an inhibitor of RNA polymerase II, through the Mal-C6 linker, showcasing potent antitumor activity.
Smiles
[H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CS(=O)c3[nH]c4cc(OCCCCCCNC(=O)CCCCCN5C(=O)C=CC5=O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1
Molecular Formula
C55H78N12O17S
Molecular Weight
1211.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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