Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ceritinib dihydrochloride

Product Specifications

CAS Number

1380575-43-8

Target

ALK, IGF-1R

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9999

Bioactivity

Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase (IC50 of 200 pM) and also inhibits IGF-1R, InsR, and STK22D [IC50 values of 8, 7, and 23 nM, respectively], demonstrating significant antitumor potency.

Smiles

Cl.Cl.CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

Molecular Formula

C28H38Cl3N5O3S

Molecular Weight

631.06

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Uncoated Mouse NGAL (Neutrophil Gelatinase Associated Lipocalin) ELISA Kit
E-UNEL-M0084-01 5x 96 Tests

Uncoated Mouse NGAL (Neutrophil Gelatinase Associated Lipocalin) ELISA Kit

Sign In for Pricing
View Details
Uncoated Mouse NGAL (Neutrophil Gelatinase Associated Lipocalin) ELISA Kit
E-UNEL-M0084-02 15x 96 Tests

Uncoated Mouse NGAL (Neutrophil Gelatinase Associated Lipocalin) ELISA Kit

Sign In for Pricing
View Details
SPINK2 (NM_021114) Human Over-expression Lysate
LC402836 20 µg

SPINK2 (NM_021114) Human Over-expression Lysate

Sign In for Pricing
View Details
WDR77 Mouse Monoclonal Antibody [Clone ID: OTI5E9]
CF809719 100 µg

WDR77 Mouse Monoclonal Antibody [Clone ID: OTI5E9]

Sign In for Pricing
View Details
Tissue FFPE Sections, Prostate
CS804133 5x 5 µm

Tissue FFPE Sections, Prostate

Sign In for Pricing
View Details
UBAP1 (NM_016525) Human Over-expression Lysate
LC402559 20 µg

UBAP1 (NM_016525) Human Over-expression Lysate

Sign In for Pricing
View Details